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There are three types of helminths of the Anisakidae family whose larvae cause human disease: Anisakis simplex, Pseudoterranova and Contracaectim. Most often there are cases of human infection with larvae of the first two species.
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The first case of human infection with helminth fam. Anisakidae has been recorded in the Netherlands.

Today, Anisakiasis is found throughout the world, but is more common in places where raw fish is eaten, such as Japan, the Pacific coast of South America, and the Netherlands.

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It should be noted that humans are incidental hosts and are not needed to complete the worm's life cycle in nature.

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Morphology of Reglan agent of Lifeny cycle Ways of human infection Anisakidosis of fish Symptoms Diagnosis Treatment Prevention. Anisakid are intestinal nematodes, non-segmented, cylindrical worms. The body has an oral and anus, as well as a gastrointestinal tract, which includes the esophagus, ventricle, and intestines.

Anisakid larvae can be spiral or elongated and reach a length of 50 mm and a diameter of 1 to 2 mm. The main hosts are marine mammals (dolphins, whales, seals, walruses) the first is crustaceans, usually from the euphausian order; Metoclopramide - marine and anadromous fish (salmon, cod, sardines, herring, etc.), squid, cuttlefish. Occasional hosts are humans, predatory land animals that feed on raw fish.

Adult Anisakis simplex and Pseudoterranova decipiens live in the stomach of marine mammals. Eggs from adult females are passed in the faeces. Larvae of the first stage are formed after the eggs fall into the water. There they develop into second-stage larvae, which are then released from the eggs and become free-swimming. The larvae released from the eggs are absorbed by the crustaceans and develop into third stage larvae.

The crustaceans are eaten by fish and squid, where the larvae migrate from the intestines to the abdominal cavity and grow up to 3 cm in length.
When fish or squid containing third-stage larvae are ingested by marine mammals, the larvae develop into adult worms.
Adult females produce eggs that are hatched by marine mammals into the environment.
Humans become infected with the larvae by eating raw, infected marine fish such as cod, halibut, tuna, sardines, mackerel, and greenlings.
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After entering the human body, the larva penetrates the mucous layers of Metoclopramide tract and causes symptoms of anisakiasis. Because humans are accidental hosts, the larva dies in the human body without developing into an adult worm.

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Reglan in fish can be seen with the naked eye. Worm larvae look like small (1-5 cm), twisted worms of light color, or are stained with blood.

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An example is in the photo below. Anisakid in hake meat. The larvae usually move there after the death of the fish, before that being in the abdominal cavity.

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Anisakides affect human health in two ways: through intestinal disorders; through an allergic reaction.

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Symptoms of acute gastric anisakiasis include sudden epigastric pain, diarrhea, vomiting, and nausea. The time required for the onset of clinical symptoms of intestinal anisakiasis is in most cases 48 hours, and the duration of abdominal pain, nausea and/or vomiting, and diarrhea is approximately 1 to 5 days. These manifestations usually go away on their own without requiring special treatment.

Allergic rash in anisakiasis
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